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This book provides readers an overview of emerging trends in the radiation detection field. Detailed in many of the chapters are specific aspects of radiation detectors, including comprehensive reviews of the historical development, and current state of each topic. The authors particularly cover emerging detection materials and detectors. High-Z materials like CdTe, CZT and GaAs offer the best implementation possibility of direct conversion X-ray detectors and are covered in this book. The authors discuss material challenges, detector operation physics and technology, and readout integrated circuits required to detect signals processes by high-Z sensors. Authors also contrast these emerging technologies with more established ones based on scintillator materials.