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Deciphering The Role of Succinate Dehydrogenase in Drug Discovery: SDH in Drug Discovery.
・ISBN 978-981-9668-33-5 paper EUR 199.99
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| 著者・編者 | Patil, Vaishali Manikrao / Kumar, Dileep / Gupta, Satya P. (eds.), |
|---|---|
| 出版社 | (Springer Nature Switzerland AG, SZ) |
| 出版年月 | 2026 |
| ページ数 | 298 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A05-85324＞ |
解説
The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and regulation mechanisms to its deficiency and its implications in related disorders. It also encompasses the impact of SDH in obstructive pulmonary disorders, discussing its potential contributions and implications. It explores the design and development of SDH inhibitors as potent agent against fungal infections. It further examines the relationship between SDH mutations and cancer development, linking genetic alterations to tumorigenesis.
The book focuses on therapeutic strategies and highlights the role of SDH in managing gastrointestinal tumors, neurodegenerative disorders, and aging-related diseases. It navigates through the challenges and prospects of utilizing SDH as a target for therapeutic interventions. The book also dives into the diagnostic aspects of SDH defects, elucidating their implications and potential diagnostic investigations. It serves as a comprehensive guide to unravel SDH's functions, dysfunctions, and therapeutic potentials.
By amalgamating diverse areas such as enzymology, genetics, pharmacology, and disease management, this book emerges as an invaluable resource for researchers, clinicians, and students alike.