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Actin-Binding Proteins and Disease. 2008 ed.
・ISBN 978-0-387-71747-0 hard EUR 199.99
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| 著者・編者 | dos Remedios, Cris / Chhabra, Deepak (eds.), |
|---|---|
| シリーズ | (Protein Reviews) |
| 出版社 | (Springer-Verlag New York Inc., US) |
| 出版年月 | 2007 |
| ページ数 | 348 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A05-55906＞ |
解説
Actin is a ubiquitous protein present in high concentrations in virtually all cells. It's assembly and disassembly is modulated by more than 100 actin-binding proteins. These interactions are essential for a variety of important cellular processes including cell division, gene expression and motility.
There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders.
This volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole. Additionally, clinicians will be interested because the book explains the role of cytoskeletal proteins in various diseases, including cancer and immune system disorders.