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Lysosomes. 2005 ed.

Lysosomes. 2005 ed.

・ISBN 978-0-387-25562-0 hard EUR 149.99

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お気に入り
著者・編者Saftig, Paul (ed.),
シリーズ (Medical Intelligence Unit)
出版社 (Springer-Verlag New York Inc., US)
出版年月2005
ページ数197 pp.
言語ENG
ニュース番号<A05-50190>

解説

Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment.

This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases. In addition to these classical topics, new insights into lysosomal functions are covered by chapters dealing with specialized lysosomes involved in bone resorption and plasma membrane repair, the lysosomal transciptome, and proteome and the emerging role of lysosomes in special forms of autophagy.

This book will provide readers with a comprehensive overview into how this fascinating organelle works and how research in the field is developing.