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Leucine-Rich Repeat Kinase 2 (LRRK2). 2017 ed.
・ISBN 978-3-319-49967-3 hard EUR 149.99
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お気に入り
★★★
| 著者・編者 | Rideout, Hardy J. (ed.), |
|---|---|
| シリーズ | (Advances in Neurobiology) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2017 |
| ページ数 | 271 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A05-49703＞ |
解説
This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.