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商品詳細
The Future of HIV-1 Therapeutics: Resistance Is Futile?. Softcover reprint of the original 1st ed. 2015
・ISBN 978-3-319-37450-5 paper EUR 99.99
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| 著者・編者 | Torbett, Bruce E. / Goodsell, David S. / Richman, Douglas D. (eds.), |
|---|---|
| シリーズ | (Current Topics in Microbiology and Immunology) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2016 |
| ページ数 | 254 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A05-49564＞ |
解説
This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.