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MicroRNAs: Key Regulators of Oncogenesis. Softcover reprint of the original 1st ed. 2014
・ISBN 978-3-319-37613-4 paper EUR 149.99
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| 著者・編者 | Babashah, Sadegh (ed.), |
|---|---|
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2016 |
| ページ数 | 433 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A05-48347＞ |
解説
Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs have a crucial function in oncogenesis by regulating cell proliferation and apoptosis as oncogenes or tumor suppressors. The expression signatures of miRNAs provide exciting opportunities in the diagnosis, prognosis and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in oncogenesis, the potential of using these small RNAs as therapeutic targets opens up new opportunities for cancer therapy by either inhibiting or augmenting their activity.