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Systems Analysis of Human Multigene Disorders. 2014 ed.
・ISBN 978-1-4614-8777-7 hard EUR 99.99
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| 著者・編者 | Maltsev, Natalia / Rzhetsky, Andrey / Gilliam, T. Conrad (eds.), |
|---|---|
| シリーズ | (Advances in Experimental Medicine and Biology) |
| 出版社 | (Springer-Verlag New York Inc., US) |
| 出版年月 | 2013 |
| ページ数 | 122 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A05-46294＞ |
解説
Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.