株式会社極東書店トップ商品一覧Phenotypes and Genotypes: The Search for Influential Genes. 1st ed. 2016

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Phenotypes and Genotypes: The Search for Influential Genes. 1st ed. 2016

Phenotypes and Genotypes: The Search for Influential Genes. 1st ed. 2016

・ISBN 978-1-4471-5309-2 hard EUR 99.99

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お気に入り
著者・編者Frommlet, Florian / Bogdan, Malgorzata / Ramsey, David,
シリーズ (Computational Biology)
出版社 (Springer London Ltd, UK)
出版年月2016
ページ数222 pp.
言語ENG
ニュース番号<A05-46193>

解説

This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.