株式会社極東書店トップ商品一覧The UNC-53-mediated Interactome: Analysis of its Role in the Generation of the C. elegans Connectome.

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The UNC-53-mediated Interactome: Analysis of its Role in the Generation of the C. elegans Connectome.

The UNC-53-mediated Interactome: Analysis of its Role in the Generation of the C. elegans Connectome.

・ISBN 978-3-319-07826-7 paper EUR 49.99

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お気に入り
著者・編者Pandey, Amita / Pandey, Girdhar K.,
シリーズ (SpringerBriefs in Neuroscience)
出版社 (Springer International Publishing AG, SZ)
出版年月2014
ページ数87 pp.
言語ENG
ニュース番号<A05-38486>

解説

This book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in turn will help to find cures to various neural and other disorders.?

In nematodes there are two types of guidance systems, including DV and AP guidance. The signaling process that guides the growth cones along the DV axis has remained intact in both vertebrates and invertebrates. The adaptor protein UNC-53 appears to play a part in migration along the AP axis in both worms and their human homologs. "Neuron Navigators" (NAV) are also involved in nervous system development

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