株式会社極東書店トップ商品一覧Genes and Mechanisms in Vertebrate Sex Determination. Softcover reprint of the original 1st ed. 2001

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Genes and Mechanisms in Vertebrate Sex Determination. Softcover reprint of the original 1st ed. 2001

Genes and Mechanisms in Vertebrate Sex Determination. Softcover reprint of the original 1st ed. 2001

・ISBN 978-3-0348-7783-1 paper EUR 49.99

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お気に入り
著者・編者Scherer, Gerd / Schmid, Michael (eds.),
シリーズ (Experientia Supplementum)
出版社 (Springer Basel, SZ)
出版年月2013
ページ数205 pp.
言語ENG
ニュース番号<A05-25915>

解説

Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.