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This book offers a set of case studies exemplifying the broad range of statis- tical science used in environmental studies and application. The case studies can be used for graduate courses in environmental statistics, as a resource for courses in statistics using genuine examples to illustrate statistical methodol- ogy and theory, and for courses in environmental science. Not only are these studies valuable for teaching about an essential cross-disciplinary activity but they can also be used to spur new research along directions exposed in these examples. The studies reported here resulted from a program of research carried on by the National Institute of Statistical Sciences (NISS) during the years 1992- 1996. NISS was created in 1991 as an initiative of the national statistics or- ganizations, with the mission to renew and focus efforts of statistical science on important cross-disciplinary problems. One of NISS' first projects was a cooperative research effort with the U.S. Environmental Protection Agency (EPA) on problems of great interest to environmental science and regulation, surely one of today's most important cross-disciplinary activities. With the support and encouragement of Gary Foley, Director of the (then) U.S. EPA Atmospheric Research and Exposure Assessment Laboratory, a project and a research team were assembled by NISS that pursued a program which produced a set of results and products from which this book was drawn.