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When reproduction defied certainty, it unsettled medicine, law, and belief. This book reveals how ambiguous pregnancies reshaped knowledge, emotion, and the cultural meaning of conception across centuries. Across the long duree of the early-modern period, British medical practitioners and society at large were preoccupied with the elusive phenomenon of "false generation"-a term encompassing false conceptions, molae, moles, and spurious pregnancies. These non-foetal pregnancies, often indistinguishable from true gestations, generated profound uncertainty in medical, legal, and theological thought. Drawing on sources ranging from anatomical treatises and midwifery manuals to women's letters, diaries, and court records, Donaghy traces how false generation shaped reproductive knowledge and understandings of the embodied experience. Through case studies such as Mary I and Joanna Southcott, the book highlights how reproductive ambiguity was not merely a private ordeal but a public and intellectual crisis. Engaging with figures like Galen, Jean Fernel, Francois Valleriola, and Frederik Ruysch, the book situates British debates within wider contemporaneous European contexts as well as a transhistorical development of medical knowledge. By foregrounding uncertainty as both an emotional and conceptual force, this monograph contributes to the history of emotions, knowledge, and the body. It offers a field-defining account of how false generation unsettled assumptions about life, conception, and pregnancy, and how these ideas evolved into modern categories such as molar pregnancy. The book speaks directly to current debates in reproductive justice and healthcare, while presenting a compelling case for the historical contingency of reproductive knowledge and the diverse ways it has been shaped by cultural, scientific, and experiential factors.