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The Retina and Circadian Rhythms. 2014 ed.
・ISBN 978-1-4614-9612-0 hard EUR 149.99
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| 著者・編者 | Tosini, Gianluca / Iuvone, P. Michael / McMahon, Douglas G. / Collin, Shaun P. (eds.), |
|---|---|
| シリーズ | (Springer Series in Vision Research) |
| 出版社 | (Springer-Verlag New York Inc., US) |
| 出版年月 | 2014 |
| ページ数 | 238 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A04-95623＞ |
解説
Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.