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This monograph contains the proceedings of an International Symposium on the Pathophysiology of Cere- bral Energy Metabolism which was held at the University of Belgrade School of Medicine, September 19-22, 1977. The purpose of the symposium was to promote an interdisciplinary discussion on energy demand in the brain in pathophysiological states, particularly with regard to cessation of blood flow, epilepsy, and para- doxical sleep disturbances. Doctors W. F. Caveness, I. Klatzo, B. B. Mrsulja, Lj. M. Rakie, and v. Susie served as an advisory board and helped to plan the sci- entific program. The papers which were presented covered neurophysiological, neurochemical, morphological, and clinical approaches to the topics. The Editors v CONTENTS Introductory Remarks 1 J. Ristic Pathophysiology of Cerebral Ischemia * * * * * * 5 K. -A. Hossmann The Interpretation of Ultrastructural Abnormalities in Cerebral Ischemia 19 J. H. Garcia, A. S. Lossinsky, K. Donger, and F. C. Kauffman Short-Term Unilateral Ischemia in Gerbils: A Reevaluation ***** 33 N. Murakami, W. D. Lust, A. B. Wheaton, and J. V. Passonneau Some New Aspects of the Pathochemistry 47 of the Post-Ischemic Period * * * * * B. B. Mrsulja Blood Flow, Oxygen, and Electrical Dynamics in Cerebral Ischemia 61 R. Cohn, B. J. Sussman, I. Klatzo, and J. F. Turman Cytochemistry of Hippocampus Following 73 Cerebral Ischemia * * ** ***** B. J. Mr~ulja, M. Spatz, and I.