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Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis. Softcover reprint of the original 1st ed. 2003
・ISBN 978-1-4613-5025-5 paper EUR 99.99
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| 著者・編者 | Harrigan, George G. / Goodacre, Royston (eds.), |
|---|---|
| 出版社 | (Springer-Verlag New York Inc., US) |
| 出版年月 | 2012 |
| ページ数 | 335 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A04-78161＞ |
解説
It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.