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商品詳細
Synthetic and Biophysical Studies on the Tridachiahydropyrone Family of Natural Products. Softcover reprint of the original 1st ed. 2016
・ISBN 978-3-319-36981-5 paper EUR 99.99
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| 著者・編者 | Powell, Kimberley Jade, |
|---|---|
| シリーズ | (Springer Theses) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2016 |
| ページ数 | 136 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A04-60875＞ |
解説
This thesis addresses fundamental scientific questions such as:
How are complex natural products synthesized in vivo?
Can we replicate these conditions in a laboratory environment?
What is the biological function of such secondary metabolites?
What are the biological origins of chirality?
These issues are explored in an accessible manner using a multidisciplinary approach spanning chemistry, biology and physics to investigate an interesting family of complex natural products isolated from marine molluscs - the tridachiahydropyrones.
The work has achieved:
Elegant biomimetic syntheses of a number of the tridachiahydropyrone compounds in vitro using organic synthesis techniques
The characterization of the interactions between these compounds and a range of model membrane systems using a series of fluorescence spectroscopic studies
The investigation of the antioxidant and photoprotective properties of the compounds by means of biophysical assay techniques
The synthesis of tridachiahydropyrone utilizing the model membrane systems as biomimetic reaction media.