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Bone Regulators and Osteoporosis Therapy. 1st ed. 2020
・ISBN 978-3-030-57377-5 hard EUR 149.99
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| 著者・編者 | Stern, Paula H. (ed.), |
|---|---|
| シリーズ | (Handbook of Experimental Pharmacology) |
| 出版社 | (Springer Nature Switzerland AG, SZ) |
| 出版年月 | 2020 |
| ページ数 | 518 pp. |
| 言語 | ENG |
| ニュース番号 | <A04-60646> |
解説
This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.