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Repeat Amino Acid Sequences in Proteins: Biochemical and Medical Consequences.
・ISBN 978-1-032-82445-1 hard GB£ 145.99
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| 著者・編者 | N. Uversky, Vladimir / Gupta, Munishwar Nath (eds.), |
|---|---|
| 出版社 | (CRC Press, UK) |
| 出版年月 | 2025 |
| ページ数 | 172 pp. |
| 言語 | ENG |
| ニュース番号 | <A04-59661> |
解説
Repeat amino acid sequences are important in protein structure, disorder, function and evolution. Repeats of some amino acids exist in proteomes across species.
This volume highlights:
- Which repeat sequences have pathogenic consequences and why?
- Repeats which lead to surface hydrophobic clusters and their importance
- Role of aromatic amino acid clusters in protein-protein and protein-drug interactions
- Cell-penetrating peptides and Elastin-like peptides
- Unusual phenomenon of fluorescence observed with repeats of some non-aromatic amino acids
- The use of residue cluster classes to represent protein structure and model structure-function relationships.