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RNA Therapeutics: From siRNA to mRNA Innovations.
・ISBN 978-1-0716-4741-7 hard EUR 179.99
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| 著者・編者 | Sioud, Mouldy (ed.), |
|---|---|
| シリーズ | (Methods in Molecular Biology) |
| 出版社 | (Springer-Verlag New York Inc., US) |
| 出版年月 | 2025 |
| ページ数 | 504 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A04-52275＞ |
解説
This book provides an overview of RNA-based technologies, covering their mechanisms, therapeutic applications, and challenges. Chapters explore therapeutic RNAs, RNA stability, mRNA vaccine formulation, strategies to overcome immunogenicity, delivery hurdles, mRNA-based cancer immunotherapy, CAR and TCR T cell therapies, and RNA interference. Additional chapters examine RNA delivery systems such as lipid nanoparticles, nanotubular structures and extracellular vesicles. Written in the highly successful Methods in Molecular Biology series format, the chapters include brief introductions to the material, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and a Notes section which highlights tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, RNA Therapeutics: From siRNA to mRNA Innovations aims to be comprehensive guide for researchers in the field.