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A growing tension between the United States and Great Britain permeates the 236 letters printed in Volume 16 of Adams Family Correspondence. The Embargo Act of 1807 cut off trade with the British in response to the harassment of American ships. John and Abigail Adams witnessed their neighbors' ensuing economic hardships and felt the sting of knowing that their son played a role in its passage. The efforts of US Senator John Quincy Adams to balance conscience with party and family loyalties are revealed in earnest correspondence, culminating in his resignation in the face of withering Federalist criticism. Louisa Catherine Adams's loyalties were always with her senator husband, though her attentions were focused on raising their children. Family concerns also occupied Thomas Boylston Adams. He married Ann Harrod, and together they added two children to the growing flock under Abigail's wing at Peacefield.

Farther afield was the Adamses' daughter, Nabby, who from New York shepherded her maturing sons through school and into adulthood. Nabby's son William was caught up in foreign intrigue when he joined an expedition of Francisco de Miranda aimed at liberating Venezuela from Spanish rule. To the relief of all the Adamses, William safely returned home. In the background of all these activities was the concern of the Adamses and of all Americans who wondered if the young republic would survive a military test with Britain. The letters printed in this volume tell these stories and more, providing invaluable commentary by the people who again experienced uncertain days in the early American republic.