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Therapeutic Intranasal Delivery for Stroke and Neurological Disorders. 2019 ed.
・ISBN 978-3-030-16713-4 hard EUR 129.99
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| 著者・編者 | Chen, Jun / Wang, Jian / Wei, Ling / Zhang, John H. (eds.), |
|---|---|
| シリーズ | (Springer Series in Translational Stroke Research) |
| 出版社 | (Springer Nature Switzerland AG, SZ) |
| 出版年月 | 2019 |
| ページ数 | 153 pp. |
| 言語 | ENG |
| ニュース番号 | <A03-94305> |
解説
The blood-brain-barrier serves to encapsulate and protect the central nervous system, but it also presents a major barricade to therapeutic drug delivery. Poor penetration is the most common hurdle to translating a promising experimental therapy that uses invasive delivery methods to a clinically useful application. In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the blood-brain-barrier and has led to some important advances in translational research for stroke and other neurological diseases. The proposed book will bring together reports from various labs around the world who have had successes in pre-clinical studies of intranasal therapies for various diseases including adult and perinatal stroke, Alzheimer's, Parkinson's, and others.?