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Molecular Biology of Long Non-coding RNAs. Second Edition 2019
・ISBN 978-3-030-17085-1 hard EUR 149.99
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| 著者・編者 | Khalil, Ahmad M. (ed.), |
|---|---|
| 出版社 | (Springer Nature Switzerland AG, SZ) |
| 出版年月 | 2019 |
| ページ数 | 187 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A03-92976＞ |
解説
This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.