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For decades now, the Asian region has been in the process of transforming from a manufacturing center of the global economy to an innovation booster for the knowledge and digital economy. Asia has emerged as an innovation powerhouse. Among Asian economies, the East Asia region has made great efforts to stimulate investment in innovation through numerous support policies aimed at fostering R&D investment, developing innovation ecosystems (in particular to support startups), training a highperformance workforce, and strengthening academy-industry-government collaboration. These efforts have resulted in “economic miracles”, transforming the East Asian region into home to some of the world’s largest economies. This book provides a detailed overview of the determinants of innovation systems in East Asia, including efforts from academia, industry, and government, as well as the evolution of innovation models towards sustainable development.