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This book offers the authors to share their opinion, news, research, reviews, and ideas on different aspects of biotechnology such as medical, plant biotechnology, food biotechnology, bioinformatic applications, systems biology, and biomedical engineering. World has witnessed the potential impact of biotechnology in various sectors. The ever-evolving nature of biotechnology and bioinformatics has resulted in an exponential increase in biotech entrepreneurship, industry-wide innovation, and development of novel technologies. Additionally, computational advancements including artificial intelligence, next generation sequencing, big data approaches, and complex algorithms have opened opportunities to understand the complex mechanisms and cellular behavior. The utility of this field has been appreciated worldwide; therefore, evaluating its applications, advancements, possibilities, challenges, ethics, and multidimensional utility will benefit scientific and non-scientific community for future applications.