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商品詳細
Cardiomyocytes - Active Players in Cardiac Disease. Softcover Reprint of the Original 1st 2016 ed.
・ISBN 978-3-319-80999-1 paper EUR 149.99
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| 著者・編者 | Schlueter, Klaus-Dieter (ed.), |
|---|---|
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2018 |
| ページ数 | 278 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A03-73263＞ |
解説
This book summarizes our current understanding about the biology and patho-biology of cardiomyocytes and depicts common techniques for the study of these cells. The book is divided into two parts; the first part provides insight into role and function of cardiomyocytes under normal conditions and describes embryogenesis and differentiation, in the second part the role of cardiomyocytes in aging and disease is discussed and cellular responses under stress conditions illustrated. Cardiomyocytes represent the main mass of the heart, and cellular malfunction directly modifies heart function leading to subsequent heart failure. As such, cardiomyocytes are causative involved in the main reasons of heart failure, such as post-infarct remodeling, hypertensive heart disease, idiopathic heart failure, and interactions with other co-morbidities such as diabetes. On the other hand, cardiomyocytes are necessarily target of therapy. Therefore, a precise understanding of cardiomyocytes biology is a pre-requisite for proper disease treatment and evidence based medicine.
The book is written for cell biologists, pharmacologists and biomedical researchers specialized in cardiac and vascular biology.