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Proteinkinase Inhibitors. 1st ed. 2021
・ISBN 978-3-030-68179-1 hard EUR 139.99
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| 著者・編者 | Laufer, Stefan (ed.), |
|---|---|
| シリーズ | (Topics in Medicinal Chemistry) |
| 出版社 | (Springer Nature Switzerland AG, SZ) |
| 出版年月 | 2021 |
| ページ数 | 256 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A03-1290＞ |
解説
This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a comprehensive and authoritative overview of the history and latest developments in the field. Chapters written by experts from industry and academia cover the function, structure and topology of Proteinkinases, molecular modelling, disclose how to achieve high level of selectivity for kinase inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book.
Given its breath, this book will appeal to medicinal chemists, students, researchers and professionals alike.