株式会社極東書店トップ商品一覧Targeted Protein Degradation: Methods and Protocols. 2021 ed.

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Targeted Protein Degradation: Methods and Protocols. 2021 ed.

Targeted Protein Degradation: Methods and Protocols. 2021 ed.

・ISBN 978-1-0716-1667-3 paper EUR 129.99

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お気に入り
著者・編者Cacace, Angela M. / Hickey, Christopher M. / Bekes, Miklos (eds.),
シリーズ (Methods in Molecular Biology 2365)
出版社 (Springer-Verlag New York Inc., US)
出版年月2021
ページ数351 pp.
言語ENG
ニュース番号<A02-77194>

解説

This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.