株式会社極東書店トップ ＞ 商品一覧 ＞ Sodium Channels, Pain, and Analgesia. 2005 ed.
商品詳細
Sodium Channels, Pain, and Analgesia. 2005 ed.
・ISBN 978-3-7643-7062-6 hard EUR 149.99
￥40,091.- (税込) ※（※）価格はご注文時の参考価格となります。
納品価格につきましては書籍の入荷時点で確定となります。
版元の原価改定、外国為替の変動等により異なる場合がございますので、予めご了承下さい。
| 著者・編者 | Coward, Kevin / Baker, Mark D. (eds.), |
|---|---|
| シリーズ | (Progress in Inflammation Research) |
| 出版社 | (Birkhauser Verlag AG, SZ) |
| 出版年月 | 2005 |
| ページ数 | 202 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A02-74258＞ |
解説
Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme.
Authors from the pharmaceutical industry discuss pharmacological approaches to the drug targeting of sodium channels, and in particular Nav1.8, exclusively expressed in nociceptive neurons. The final chapter highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are being provided by tissue specific and inducible gene knock-out technology.