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Delta Opioid Receptor Pharmacology and Therapeutic Applications. 2018 ed.
・ISBN 978-3-319-95131-7 hard EUR 159.99
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| 著者・編者 | Jutkiewicz, Emily M. (ed.), |
|---|---|
| シリーズ | (Handbook of Experimental Pharmacology) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2018 |
| ページ数 | 348 pp. |
| 言語 | ENG |
| ニュース番号 | <A02-70337> |
解説
This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed.