株式会社極東書店トップ ＞ 商品一覧 ＞ Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles. 2020 ed.
商品詳細
Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles. 2020 ed.
・ISBN 978-3-030-54079-1 paper EUR 149.99
￥40,091.- (税込) ※（※）価格はご注文時の参考価格となります。
納品価格につきましては書籍の入荷時点で確定となります。
版元の原価改定、外国為替の変動等により異なる場合がございますので、予めご了承下さい。
| 著者・編者 | Yoon, Hyung, |
|---|---|
| シリーズ | (Springer Theses) |
| 出版社 | (Springer Nature Switzerland AG, SZ) |
| 出版年月 | 2021 |
| ページ数 | 212 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A02-61454＞ |
解説
This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon-carbon bonds in high atom- and step-economy.
In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, andhighlights its synthetic utility.
Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C-H activation and ?-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.