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Rapid Cell Magnetisation Using Cationised Magnetoferritin. 1st ed. 2017
・ISBN 978-3-319-60332-2 hard EUR 99.99
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| 著者・編者 | Correia Carreira, Sara, |
|---|---|
| シリーズ | (Springer Theses) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2017 |
| ページ数 | 166 pp. |
| 言語 | ENG |
| ニュース番号 | <A02-57139> |
解説
Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.