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商品詳細
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease. Softcover Reprint of the Original 1st 2017 ed.
・ISBN 978-3-319-88453-0 paper EUR 159.99
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| 著者・編者 | Telerman, Adam / Amson, Robert (eds.), |
|---|---|
| シリーズ | (Results and Problems in Cell Differentiation) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2018 |
| ページ数 | 309 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A02-54611＞ |
解説
This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis.
In turn, the book's final section is devoted to the role of TCTP in disease, namely asthma and diverse cancers, and ultimately as a target for the treatment of malignancies. What is the common denominator between all these processes and why is TCTP necessary in order for them to occur, even in the worst case such as cancer? The book seeks to provide meaningful answers to this and other key questions. Presenting a broad and revealing view on the topic, it offers an informative guide for scientists and students alike.