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KRAS: Methods and Protocols. 2024 ed.
・ISBN 978-1-0716-3821-7 hard EUR 219.99
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| 著者・編者 | Stephen, Andrew G. / Esposito, Dominic (eds.), |
|---|---|
| シリーズ | (Methods in Molecular Biology 2797) |
| 出版社 | (Springer-Verlag New York Inc., US) |
| 出版年月 | 2024 |
| ページ数 | 365 pp. |
| 言語 | ENG |
| ニュース番号 | <A02-31344> |
解説
This volume details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, KRAS: Methods and Protocols aims to provide methods that will be instrumental in the development of future clinically approved KRAS therapeutics.