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商品詳細
Computer-Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates.
・ISBN 978-1-138-49750-4 hard GB£ 210.00
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| 著者・編者 | Eswari, Jujjvarapu Satya / Dhagat, Swasti / Yadav, Manisha, |
|---|---|
| 出版社 | (CRC Press, UK) |
| 出版年月 | 2019 |
| ページ数 | 146 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-41625＞ |
解説
Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques.
Key Features:
- Focuses on the use lipopeptides as new antimicrobial compounds
- Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field
- Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico
- Couples with courses on patents and intellectual property rights