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In the early years of COVID-19, Americans witnessed the intersection of a global pandemic, an economic collapse, and civil unrest that galvanized the country and the world and ushered in an era of unprecedented disruption. Three years later, we can begin to reflect on the experience of the pandemic and ask ourselves how the lessons of that experience can inform a healthier present and future. The Turning Point: Reflections on a Pandemic examines the first years of COVID-19 through the lens of population health, revealing a critical turning point in our engagement with key public health issues. Through a series of short, provocative essays, the authors leverage their experience as prominent public health leaders to untangle the social, economic, environmental, and political forces at work in our response to the pandemic. Combining cutting-edge data with philosophical insights, these bold and revelatory essays encourage us to broaden and sharpen our vision of health and renegotiate policies that can allow health to flourish in extraordinary-and ordinary-times.