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商品詳細
Extracellular Matrix in Tumor Biology. Softcover Reprint of the Original 1st 2017 ed.
・ISBN 978-3-319-86956-8 paper EUR 99.99
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| 著者・編者 | Brekken, Rolf A. / Stupack, Dwayne (eds.), |
|---|---|
| シリーズ | (Biology of Extracellular Matrix) |
| 出版社 | (Springer International Publishing AG, SZ) |
| 出版年月 | 2018 |
| ページ数 | 115 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A01-86962＞ |
解説
This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike.