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Name: Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression, Volume 1058.
Price: 31630 JPY
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Author: Cho-Chung, Yoon S. / Gewirtz, Alan M. / Stein, Cy A. (eds.)
ISBN: 978-1-57331-609-5

Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression, Volume 1058.

・ISBN 978-1-57331-609-5 paper US$ 135.00

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著者・編者	Cho-Chung, Yoon S. / Gewirtz, Alan M. / Stein, Cy A. (eds.),
シリーズ	(Annals of the New York Academy of Sciences)
出版社	(Wiley-Blackwell, UK)
出版年月	2006
ページ数	284 pp.
言語	ENG
ニュース番号	＜A00-99592＞

解説

The potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools are explored in this volume, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. The focus is on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides.

Specific chapters address designing better siRNAs, splice switching oligonucleotides, selective delivery of oligonucleotides, and medicinal drugs by receptor-mediated endocytosis, development of a function overriding siRNA silencing in mammalian cells, transcription factor decoys, and modified oligonucleotide hybridization and genetic insertion.

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