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Transcription Factors and Human Disease.
・ISBN 978-0-19-511239-9 hard US$ 86.00
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お気に入り
★★★
| 著者・編者 | Semenza, Gregg L., |
|---|---|
| シリーズ | (Oxford Monographs on Medical Genetics 37) |
| 出版社 | (Oxford University Press Inc, US) |
| 出版年月 | 1998 |
| ページ数 | 384 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-58106＞ |
解説
Transcription factors are essential mediators of the genetic programs that control development and physiology. This exciting book presents current knowledge of transcription factors from two viewpoints. First, the basic science of transcriptional regulation is discussed. Second, inherited human diseases attributable to mutations in DNA sequences encoding transcription factors or their cognate binding sites are described. Readers are also introduced to the involvement of transcription factors in somatic cell genetic disease (cancer) and epigenetic disease (teratogenesis).