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商品詳細
Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution.
・ISBN 978-1-4665-9486-9 hard GB£ 210.00
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| 著者・編者 | Valentine, Raymond C. / Valentine, David L., |
|---|---|
| 出版社 | (CRC Press Inc, US) |
| 出版年月 | 2014 |
| ページ数 | 259 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-52363＞ |
解説
More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman's famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging.
Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington's disease, Parkinson's disease, and traumatic brain disease in animal models of neurodegeneration.
This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.