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Itch: Mechanisms and Treatment.
・ISBN 978-1-4665-0543-8 hard GB£ 210.00
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| 著者・編者 | Carstens, E. / Akiyama, Tasuku (eds.), |
|---|---|
| シリーズ | (Frontiers in Neuroscience) |
| 出版社 | (CRC Press Inc, US) |
| 出版年月 | 2014 |
| ページ数 | 494 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-52092＞ |
解説
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain.
Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer.
Composed of contributions from distinguished researchers around the world, the book explores topics such as:
- Neuropathic itch
- Peripheral neuronal mechanism of itch
- The role of PAR-2 in neuroimmune communication and itch
- Mrgprs as itch receptors
- The role of interleukin-31 and oncostatin M in itch and neuroimmune communication
- Spinal coding of itch and pain
- Spinal microcircuits and the regulation of itch
Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.