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Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes. This book assembles and synthesizes four decades of the most important research carried out in this field. The chapters focus on the latest progress made on translating the knowledge gained to specific treatment modalities, including approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system and enhancing epithelial tissue repair. The book will inform and update specialists, clinical practitioners and those studying the potential for commercial applications.