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This text on electron microscopy in viral diagnosis is an invaluable reference investigators interested in the detection of viruses or viral subcomponents in liquid preparations or in thin sectioned cells. It contains an extensive collection of negative stain, thin section, and immunolabelled electron micrographs useful for reference viral diagnosis. The salient features of the replication of many virus families are presented in schematic form and all viruses now known to cause disease in humans, including the recently recognized human retroviruses, are described in separate chapter.