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Increasing capacity at ports and goods movement in the supply chain in general, while also satisfying environmental, economic, political, labor union, and other constraints is, arguably, the greatest challenge of modern transportation. With space at a premium and costs through the roof, it is increasingly obvious that the traditional solutions are not feasible in the short- or even medium-term. However, advances in information technology, telecommunications, data management, and computation tools, coupled with recent research in systems optimization and control, may provide promising new approaches.