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商品詳細
Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective.
・ISBN 978-0-367-39560-5 paper GB£ 70.99
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お気に入り
★★★
| 著者・編者 | Kimko, Hui / Duffull, Stephen B. (eds.), |
|---|---|
| 出版社 | (CRC Press, UK) |
| 出版年月 | 2019 |
| ページ数 | 424 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-40350＞ |
解説
Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.