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Target Organ Toxicity: Volume 2.
・ISBN 978-0-367-25871-9 hard GB£ 210.00
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| 著者・編者 | Cohen, Gerald M. (ed.), |
|---|---|
| シリーズ | (Routledge Revivals) |
| 出版社 | (CRC Press, UK) |
| 出版年月 | 2020 |
| ページ数 | 234 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-40312＞ |
解説
First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.