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The Blood-Brain Barrier and Drug Delivery to the CNS

The Blood-Brain Barrier and Drug Delivery to the CNS

・ISBN 978-0-8247-0394-3 hard GB£ 170.00

￥53,856.- (税込) ※（※）価格はご注文時の参考価格となります。
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著者・編者Bradbury, Michael / Begley, David / Kreuter, Jorg (eds.),
出版社 (CRC Press Inc, US)
出版年月2000
ページ数264 pp.
言語ENG
ニュース番号＜A00-35128＞

解説

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research.
Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques.
A concise reference with reviews from nearly 40 international specialists in diverse fields, The Blood-Brain Barrier and Drug Delivery to the CNS

  • assesses the properties of the blood-brain barrier to determine and measure drug permeability in animals and humans
  • presents techniques to predict successful drug uptake through in vitro systems or by computation of physicochemical parameters
  • examines the multidrug resistance protein P-glycoprotein as a natural transporter
  • analyzes current drug designs to known requirements for transport
  • looks at drug delivery systems for the brain
  • and much more!
    Densely packed with over 800 literature references, drawings, photographs, x-rays, tables, and equations, The Blood-Brain Barrier and Drug Delivery to the CNS is a vital addition to the bookshelves of biochemists, pharmacists, clinical and research pharmacologists, neuroscientists and neurologists, and graduate and medical school students in these disciplines.