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Single-Molecule Studies of Nucleic Acids and Their Proteins.
・ISBN 978-0-19-853092-3 hard GB£ 79.00
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| 著者・編者 | Bensimon, David / Croquette, Vincent / Allemand, Jean-FranA?ois / Michalet, Xavier / Strick, Terence, |
|---|---|
| シリーズ | (Oxford Graduate Texts) |
| 出版社 | (Oxford University Press, UK) |
| 出版年月 | 2018 |
| ページ数 | 240 pp. |
| 言語 | ENG |
| ニュース番号 | ＜A00-20202＞ |
解説
This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.