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Information Systems Innovation for Nursing, the newest entry in the Sage Series on Nursing Administration, offers a broad range of discussions concerning health care information systems. Section I explores the implications of working in a computer-based environment, looking at the opportunities it presents for advanced nursing practice, for managing patient care, and for administering outcomes research. Different kinds of computer knowledge applications are examined in Section II. Topics include linkages for nurse administrators, computer-augmented performance evaluation, information access for research-based practice, and communication structure enhancement for nursing research. Section III offers a variety of suggestions related to changing health care settings to accommodate the advantages of computer technology. The chapters examine computer-based information needs and implementation in a major medical center, a rural health care delivery network, the Veterans Administration infrastructure, and in community settings. This section also demonstrates the cost effectiveness of computer technology in caring for AlzheimerAEs patients and shows how clinical management nationally can be maximized through automation of the Federal Minimum Data Set. Information Systems Innovation for Nursing will be of interest to graduate students, scholars, and advanced practice clinicians in nursing trends, administration, management, and informatics.