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Different people feel different emotions when they are diagnosed with cancer. Both today and a century ago, fear and hope, shame and disgust, sadness and joy are and were the emotions experienced by many cancer patients and their loved ones. But these emotions do not just have significance for the people who feel them. They have also exerted a surprisingly profound influence on how hospitals and laboratories dealt with cancer, how early detection campaigns portrayed it, and how doctors talked about it with their patients. Bettina Hitzer details the history of cancer and emotions in twentieth-century Germany and thus follows the cancer-associated transformations of emotional regimes, emotional politics, and emotional experiences through five different political systems. In doing so, the study underscores that political caesuras resonate in the immediate corporeality of the history of emotions.